Which herb has bronchodilator, hypotensive, and antispasmodic actions?

Prepare for the NPLEX II Botanical Medicine Test with comprehensive flashcards and multiple-choice questions. Each question includes hints and detailed explanations to optimize your study session. Ace your NPLEX II with confidence!

Multiple Choice

Which herb has bronchodilator, hypotensive, and antispasmodic actions?

Explanation:
Coleus forskohlii fits these actions because its active constituent forskolin directly stimulates adenylate cyclase, increasing intracellular cAMP. Higher cAMP in smooth muscle causes relaxation, leading to bronchodilation in the airways, relaxation of vascular smooth muscle (lowering blood pressure), and antispasmodic effects on other smooth muscles. This combination of bronchodilatory, hypotensive, and antispasmodic actions is characteristic of forskolin’s mechanism. The other herbs don’t share this profile: Corydalis ambigua is mainly an analgesic/sedative, Commiphora mukul (guggul) focuses on lipid metabolism and anti-inflammatory effects, and cinnamon is primarily a warming, digestive herb with no strong bronchodilator/hypotensive/antispasmodic triad.

Coleus forskohlii fits these actions because its active constituent forskolin directly stimulates adenylate cyclase, increasing intracellular cAMP. Higher cAMP in smooth muscle causes relaxation, leading to bronchodilation in the airways, relaxation of vascular smooth muscle (lowering blood pressure), and antispasmodic effects on other smooth muscles. This combination of bronchodilatory, hypotensive, and antispasmodic actions is characteristic of forskolin’s mechanism. The other herbs don’t share this profile: Corydalis ambigua is mainly an analgesic/sedative, Commiphora mukul (guggul) focuses on lipid metabolism and anti-inflammatory effects, and cinnamon is primarily a warming, digestive herb with no strong bronchodilator/hypotensive/antispasmodic triad.

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